Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9934696 | 0.81 | VDR (0.37) | VDR | |
| SCHEMBL28008537 | 0.80 | MCHR1 (0.36) | VDR | |
| SCHEMBL12004163 | 0.72 | VDR (0.39) | VDR | |
| SCHEMBL28697935 | 0.71 | VDR (0.38) | VDR | |
| SCHEMBL15791367 | 0.67 | VDR (0.39) | VDR | |
| SCHEMBL12003963 | 0.67 | MCHR1 (0.40) | — | |
| SCHEMBL12465636 | 0.66 | L3MBTL1 (0.54) | MAPT | |
| SCHEMBL9935135 | 0.66 | VDR (0.39) | VDRMAPT | |
| SCHEMBL22683485 | 0.65 | VDR (0.38) | VDRMAPT | |
| SCHEMBL20487629 | 0.64 | LOXL2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103517898-B | Novel 3-hydroxyisothiazole 1-oxide derivatives | MOCHIDA PHARMACEUTICAL CO.,LTD. (JP) | 2015-09-30 | — | — | CN | disclosed |