SCHEMBL28035508

SCHEMBL28035508

COc1cc(C(=O)C2CCCCC2)ccc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.60
RAB9A P51151 2/20 0.60
MEN1 O00255 2/20 0.60
SLC22A6 Q4U2R8 1/20 0.60
SLC22A8 Q8TCC7 1/20 0.60
DUSP3 P51452 5/20 0.59
ALDH1A1 P00352 5/20 0.59
PTPN7 P35236 4/20 0.59
HPGD P15428 4/20 0.59
MAPT P10636 2/20 0.59
LMNA P02545 1/20 0.59
PDE4B Q07343 1/20 0.59
PDE4D Q08499 1/20 0.59
HTT P42858 1/20 0.58
HSD17B10 Q99714 2/20 0.54
PTPN5 P54829 1/20 0.54
PTPN11 Q06124 1/20 0.54
NPC1 O15118 1/20 0.52
GFER P55789 1/20 0.51
HSD17B2 P37059 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15684713 0.89 PDE4B (0.64) KMT2ARAB9AMEN1ALDH1A1LMNA
SCHEMBL1291777 0.87 PDE4B (0.66) KMT2ARAB9AMEN1ALDH1A1LMNA
SCHEMBL27264231 0.85 PDE4D (0.56) KMT2ARAB9AALDH1A1HPGDLMNA
SCHEMBL31058497 0.82 ALDH1A1 (0.60) RAB9AALDH1A1LMNAPDE4BPDE4D
SCHEMBL24222555 0.81 SIRT5 (0.58) KMT2ARAB9AMEN1ALDH1A1PDE4B
SCHEMBL23734465 0.81 SIRT5 (0.58) KMT2ARAB9AMEN1ALDH1A1PDE4B
SCHEMBL15851060 0.81 SRD5A2 (0.50) KMT2ARAB9AMEN1LMNAPDE4B
SCHEMBL23898780 0.81 SIRT5 (0.58) KMT2ARAB9AMEN1ALDH1A1PDE4B
SCHEMBL8887975 0.81 KMT2A (0.68) KMT2ARAB9AMEN1SLC22A6SLC22A8
SCHEMBL1353467 0.81 KMT2A (0.61) KMT2ARAB9AMEN1SLC22A6SLC22A8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105037299-A 3,4-epoxy cyclohexyl methylal diol, and synthesis method and application thereof Yueyang changde chemical industry co ltd 2015-11-11 CN disclosed
CN-105016986-A (3-alkoxy-4-hydroxy)-cyclohexyl methylal diol, isomer thereof and synthesis methods and use for (3-alkoxy-4-hydroxy)- cyclohexyl methylal diol and isomer thereof Yueyang changde chemical industry co ltd 2015-11-04 CN disclosed