Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31058497 | 0.88 | ALDH1A1 (0.60) | PDE4DPDE4BALDH1A1GAAHTT | |
| SCHEMBL15684713 | 0.86 | PDE4B (0.64) | PDE4DPDE4BALDH1A1GAANPC1 | |
| SCHEMBL28035508 | 0.85 | KMT2A (0.60) | PDE4DPDE4BALDH1A1GAAHPGD | |
| SCHEMBL1291777 | 0.84 | PDE4B (0.66) | PDE4DPDE4BALDH1A1GAANPC1 | |
| SCHEMBL27818194 | 0.81 | HSD11B1 (0.56) | PDE4DPDE4BALDH1A1NPC1RAB9A | |
| SCHEMBL20202560 | 0.80 | HTT (0.63) | PDE4DPDE4BALDH1A1GAAHTT | |
| SCHEMBL23734465 | 0.78 | SIRT5 (0.58) | PDE4DPDE4BALDH1A1GAANPC1 | |
| SCHEMBL24222555 | 0.78 | SIRT5 (0.58) | PDE4DPDE4BALDH1A1GAANPC1 | |
| SCHEMBL23898780 | 0.78 | SIRT5 (0.58) | PDE4DPDE4BALDH1A1GAANPC1 | |
| SCHEMBL10413533 | 0.78 | CYP1A2 (0.61) | PDE4DPDE4BALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1022685-C | Hydrofluorene derivatives | OTSUKA PHARMA CO LTD (JP) | 1993-11-10 | — | — | CN | disclosed |