Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88480 | 0.88 | ECE1 (0.46) | ECE1MEN1KMT2APDCD1LG2CD274 | |
| SCHEMBL88481 | 0.88 | ECE1 (0.46) | ECE1MEN1KMT2APDCD1LG2CD274 | |
| SCHEMBL30406637 | 0.88 | ECE1 (0.46) | ECE1MEN1KMT2APDCD1LG2CD274 | |
| SCHEMBL2514366 | 0.80 | ECE1 (0.42) | ECE1MEN1KMT2AITGB2ICAM1 | |
| SCHEMBL8675912 | 0.80 | ECE1 (0.42) | ECE1MEN1KMT2AITGB2ICAM1 | |
| SCHEMBL9505796 | 0.78 | ECE1 (0.36) | ECE1MEN1KMT2AFOLH1RIMKLA | |
| SCHEMBL4519259 | 0.76 | CA2 (0.42) | FOLH1RIMKLANAALAD2CA2 | |
| SCHEMBL11131045 | 0.76 | CA2 (0.42) | FOLH1RIMKLANAALAD2CA2 | |
| SCHEMBL5489086 | 0.76 | CA2 (0.42) | FOLH1RIMKLANAALAD2CA2 | |
| Phenol SCHEMBL27348628 | 0.74 | ALDH1A1 (0.46) | ECE1MEN1KMT2AFOLH1ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104995516-A | Agents, kits and methods for complement factor H-related protein 1 detection | MORPHOSYS AG | 2015-10-21 | — | — | CN | disclosed |