SCHEMBL88480

SCHEMBL88480

CCNC(CC(N)=O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 2/20 0.46
ITGB2 P05107 2/20 0.40
ICAM1 P05362 2/20 0.40
ITGAL P20701 2/20 0.40
CA2 P00918 2/20 0.38
ALDH1A1 P00352 1/20 0.38
RAB9A P51151 1/20 0.38
CA1 P00915 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
PDCD1LG2 Q9BQ51 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
FOLH1 Q04609 2/20 0.36
NAALAD2 Q9Y3Q0 2/20 0.36
TGFBR1 P36897 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88481 1.00 ECE1 (0.46) ECE1ITGB2ICAM1ITGALCA2
SCHEMBL30406637 1.00 ECE1 (0.46) ECE1ITGB2ICAM1ITGALCA2
SCHEMBL28035646 0.88 ECE1 (0.39) ECE1ITGB2ICAM1ITGALCA2
Phenol SCHEMBL27348628 0.85 ALDH1A1 (0.46) ECE1ITGB2ICAM1ITGALCA2
Phenol SCHEMBL28342610 0.85 ALDH1A1 (0.46) ECE1ITGB2ICAM1ITGALCA2
SCHEMBL3856802 0.84 ECE1 (0.42) ECE1ITGB2ICAM1ITGALCA2
SCHEMBL7034111 0.84 ECE1 (0.42) ECE1ITGB2ICAM1ITGALCA2
Benzene SCHEMBL28092853 0.83 ECE1 (0.39) ECE1ITGB2ICAM1ITGALCA2
SCHEMBL1688082 0.83 ECE1 (0.40) ECE1ITGB2ICAM1ITGALCA2
SCHEMBL30089038 0.83 ECE1 (0.44) ECE1ITGB2ICAM1ITGALCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 665 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115297958-A Microcapsules coated with polysuccinimide derivatives 弗门尼舍有限公司 2022-11-04 CN claimed
CN-104045698-B Polypeptide, polypeptide derivative, medicinal salt of polypeptide and medicinal composition 深圳君圣泰生物技术有限公司 2019-04-16 CN claimed
EP-2341774-B1 TREATMENT OF NEUROBLASTOMA WITH MULTI-ARM POLYMERIC CONJUGATES OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN BELROSE PHARMA INC (US) 2013-12-04 EP claimed
US-20120322717-A9 Compounds and assays for controlling Wnt activity ENZO BIOCHEM, INC. 2012-12-20 US claimed
US-20100298200-A1 Compounds and assays for controlling Wnt activity LIU DAKAI 2010-11-25 US claimed
JP-2010524472-A 2010-07-22 JP claimed
EP-2147116-A1 STABLE RECOMBINANT ADENOSINE DEAMINASE Enzon Pharmaceuticals, Inc. (US) 2010-01-27 EP claimed
US-20090047271-A1 STABLE RECOMBINANT ADENOSINE DEAMINASE ENZON PHARMACEUTICALS, INC. (US) 2009-02-19 US claimed
WO-2008131208-A1 STABLE RECOMBINANT ADENOSINE DEAMINASE ENZON PHARMACEUTICALS, INC. (US) 2008-10-30 WO claimed
US-12600778-B2 Rage antibodies, fragments and uses thereof THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2026-04-14 US disclosed
US-12594342-B2 Method of conjugation of Cys-mAbs AMGEN INC. (US) 2026-04-07 US disclosed
US-20260077054-A1 COMBINATIONS OF ANTI-GIP ANTIBODIES AND INCRETINS AND USES THEREOF HELICORE BIOPHARMA INC (US) 2026-03-19 US disclosed
US-20260034235-A1 METHOD OF CONJUGATION OF CYS-MABS AMGEN INC. (US) 2026-02-05 US disclosed
US-20260001956-A1 METHOD OF TREATING OR AMELIORATING METABOLIC DISORDERS USING BINDING PROTEINS FOR GASTRIC INHIBITORY PEPTIDE RECEPTOR (GIPR) IN COMBINATION WITH GLP-1 AGONISTS AMGEN INC. (US) 2026-01-01 US disclosed
CN-1301155-A Stable pharmaceutical formulation of gamma-aminobutyric acid derivatives and process for preparing the same WARNER LAMBERT CO (US) 2001-06-27 CN disclosed
CN-1051769-C Peptides NOVATIS INC (CH) 2000-04-26 CN disclosed
US-5622934-A TREATING DIABETES MELLITUS HOECHST AKTIENGESELLSCHAFT (DE) 1997-04-22 US disclosed
EP-0672057-A1 ANALOGS OF PTH Novartis AG (CH) 1995-09-20 EP disclosed
CN-1099801-A Peptides SANDOZ LTD (CH) 1995-03-08 CN disclosed
WO-1994002510-A2 ANALOGS OF PTH SANDOZ LTD. (CH) 1994-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120322717-A9 Compounds and assays for controlling Wnt activity WNT1, WNT3A, WNT3 ECE1 3548/4885ITGB2 3089/4885ICAM1 3351/4885
US-12594342-B2 Method of conjugation of Cys-mAbs TST, PTMS, TMT1A ECE1 4675/4885ITGB2 140/4885ICAM1 1025/4885
US-20260034235-A1 METHOD OF CONJUGATION OF CYS-MABS CBS, GCLC, PTMS ECE1 4332/4885ITGB2 202/4885ICAM1 1028/4885
US-20260001956-A1 METHOD OF TREATING OR AMELIORATING METABOLIC DISORDERS USING BINDING PROTEINS FOR GASTRIC INHIBITORY PEPTIDE RECEPTOR (GIPR) IN COMBINATION WITH GLP-1 AGONISTS GIPR, GLP1R, IAPP ECE1 4104/4885ITGB2 2192/4885ICAM1 314/4885
US-20260077054-A1 COMBINATIONS OF ANTI-GIP ANTIBODIES AND INCRETINS AND USES THEREOF GIPR, GLP1R, GPR119 ECE1 3064/4885ITGB2 3153/4885ICAM1 393/4885
US-20100298200-A1 Compounds and assays for controlling Wnt activity WNT1, WNT3A, WNT3 ECE1 3548/4885ITGB2 3089/4885ICAM1 3351/4885
US-20090047271-A1 STABLE RECOMBINANT ADENOSINE DEAMINASE ADA, CDA, DCTD ECE1 2396/4885ITGB2 4510/4885ICAM1 3967/4885
US-12600778-B2 Rage antibodies, fragments and uses thereof IGSF11, FCGR1A, FCGR3B ECE1 3901/4885ITGB2 68/4885ICAM1 46/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.