Butylbenzyl

Butylbenzyl

SCHEMBL28035944

CCC(CC(CC)c1ccccc1C(=O)O)c1ccccc1C(=O)O.CCCCc1ccccc1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 4/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
PLK3 Q9H4B4 3/20 0.44
BRS3 P32247 3/20 0.44
DHODH Q02127 1/20 0.43
RARB P10826 1/20 0.43
EPHX2 P34913 2/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYSLTR2 Q9NS75 2/20 0.43
CYSLTR1 Q9Y271 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
RECQL P46063 1/20 0.43
KMT2A Q03164 1/20 0.43
LTB4R2 Q9NPC1 1/20 0.42
TRPV1 Q8NER1 1/20 0.42
TRPA1 O75762 1/20 0.41
TRPM2 O94759 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28035943 0.92 MCL1 (0.41) PLK1SMN1; SMN2PLK3BRS3EPHX2
Butylbenzyl SCHEMBL28035568 0.85 KMT2A (0.40) PLK1SMN1; SMN2PLK3BRS3RARB
Butylbenzyl SCHEMBL28035951 0.84 PLK1 (0.47) PLK1SMN1; SMN2PLK3BRS3DHODH
Phthalic Acid SCHEMBL3679549 0.82 PLK1 (0.57) PLK1SMN1; SMN2PLK3DHODHRARB
Isobutylbenzene SCHEMBL28035520 0.82 DHODH (0.42) DHODHRARBTRPA1
SCHEMBL13951792 0.80 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL433915 0.80 ALDH1A1 (0.52) PLK1ALDH1A1CYSLTR2CYSLTR1KDM4E
Phthalic Acid SCHEMBL28390429 0.78 PLK1 (0.61) PLK1PLK3DHODHRARBALDH1A1
SCHEMBL671032 0.78 ALDH1A1 (0.55) PLK1PLK3ALDH1A1CYSLTR2CYSLTR1
Isopropylbenzene SCHEMBL28035521 0.78 CRHBP (0.43) SMN1; SMN2DHODHALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105085746-A Catalyst component for propylene polymerization, and catalyst thereof CHINA PETROLEUM & CHEMICAL 2015-11-25 CN claimed
CN-105085726-A Catalyst component for olefin polymerization, and catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-11-25 CN claimed
CN-105085746-A Catalyst component for propylene polymerization, and catalyst thereof CHINA PETROLEUM & CHEMICAL 2015-11-25 CN disclosed
CN-105085726-A Catalyst component for olefin polymerization, and catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-11-25 CN disclosed