Isobutylbenzene

Isobutylbenzene

SCHEMBL28035520

CC(C)Cc1ccccc1.CCC(CC(CC)c1ccccc1C(=O)O)c1ccccc1C(=O)O

nearest known ligand 0.49

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.42
ACE P12821 1/20 0.42
POLB P06746 2/20 0.41
TRPA1 O75762 1/20 0.41
ALOX5 P09917 2/20 0.40
PTGS1 P23219 3/20 0.40
PTGS2 P35354 3/20 0.40
LMNA P02545 2/20 0.40
CYP2C9 P11712 2/20 0.40
AKR1C3 P42330 2/20 0.40
CXCR1 P25024 2/20 0.40
CXCR2 P25025 2/20 0.40
AKR1C2 P52895 2/20 0.40
ALB P02768 1/20 0.40
ESR1 P03372 1/20 0.40
RARB P10826 1/20 0.40
ADRB3 P13945 1/20 0.40
NFKB1 P19838 1/20 0.40
HTR2A P28223 1/20 0.40
NR1I3 Q14994 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isobutylbenzene SCHEMBL28035954 0.85 ALOX5 (0.35) DHODHACEALOX5PTGS1PTGS2
SCHEMBL28035943 0.84 MCL1 (0.41) POLBNPC1RAB9ATSHR
Isobutylbenzene SCHEMBL28035953 0.84 DHODH (0.45) DHODHACEPOLBALOX5PTGS1
Isopropylbenzene SCHEMBL28035521 0.82 CRHBP (0.43) DHODHPOLBTRPA1LMNANPC1
SCHEMBL11204390 0.82 POLB (0.42) POLBLMNARAB9ATSHR
Butylbenzyl SCHEMBL28035944 0.82 PLK1 (0.46) DHODHTRPA1RARB
SCHEMBL13951792 0.81 ALDH1A1 (0.50) POLBLMNAAKR1C3TSHR
SCHEMBL7204826 0.77 NPC1 (0.51) POLBPTGS1LMNANPC1RAB9A
SCHEMBL6876901 0.75 POLB (0.44) POLBTSHR
Isobutylbenzene SCHEMBL27955709 0.74 PTGS1 (0.59) TRPA1ALOX5PTGS1PTGS2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105085746-B Catalytic component and its catalyst for propylene polymerization 中国石油化工股份有限公司 2017-09-29 CN claimed
CN-105085746-A Catalyst component for propylene polymerization, and catalyst thereof CHINA PETROLEUM & CHEMICAL 2015-11-25 CN claimed
CN-105085726-A Catalyst component for olefin polymerization, and catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-11-25 CN claimed
CN-107868152-A A kind of catalytic component, catalyst and its application for olefinic polymerization 中国石油化工股份有限公司 2018-04-03 CN disclosed
CN-107868153-A A kind of catalytic component, catalyst and its application for olefinic polymerization 中国石油化工股份有限公司 2018-04-03 CN disclosed
CN-105085726-B A kind of catalytic component and catalyst for olefinic polymerization 中国石油化工股份有限公司 2017-11-07 CN disclosed
CN-105085746-B Catalytic component and its catalyst for propylene polymerization 中国石油化工股份有限公司 2017-09-29 CN disclosed
CN-105085746-A Catalyst component for propylene polymerization, and catalyst thereof CHINA PETROLEUM & CHEMICAL 2015-11-25 CN disclosed
CN-105085726-A Catalyst component for olefin polymerization, and catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-11-25 CN disclosed