Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15032602 | 0.87 | TDP1 (0.53) | TDP1HCAR2NOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3257142 | 0.79 | TDP1 (0.65) | TDP1HCAR2NOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29688221 | 0.79 | TDP1 (0.65) | TDP1HCAR2NOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2348903 | 0.78 | TDP1 (0.69) | TDP1HCAR2NOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22890311 | 0.77 | ALDH1A1 (0.47) | TDP1HCAR2NOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11137628 | 0.76 | TDP1 (0.61) | TDP1HCAR2NOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4574660 | 0.75 | HCAR2 (0.48) | TDP1HCAR2ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL4328723 | 0.74 | TDP1 (0.59) | TDP1HCAR2NOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13758030 | 0.74 | HCAR2 (0.44) | TDP1HCAR2ALDH1A1SMN1; SMN2MAPK1 | |
| Picloram SCHEMBL8467014 | 0.74 | TDP1 (1.00) | TDP1HCAR2NOX1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104988531-B | The method that a kind of selective dechlorination of chloro-pyridine formic acid electro-catalysis prepares pyridine carboxylic acid | 浙江工业大学 | 2017-11-07 | — | — | CN | disclosed |
| CN-104988531-A | Method for preparing picolinic acid through electro-catalysis selective dechloridation of chloropicolinicacid | UNIV ZHEJIANG TECHNOLOGY | 2015-10-21 | — | — | CN | disclosed |