Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 7/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | DDO | Q99489 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516901 | 0.93 | CA2 (0.67) | CA2HSD17B10ALDH1A1CNR1AKR1B1 | |
| SCHEMBL29560278 | 0.93 | CA2 (0.67) | CA2HSD17B10ALDH1A1CNR1AKR1B1 | |
| SCHEMBL15646965 | 0.91 | CA2 (0.65) | CA2HSD17B10ALDH1A1CNR1AKR1B1 | |
| Hydrochloric Acid SCHEMBL27675573 | 0.91 | CA2 (0.65) | CA2HSD17B10ALDH1A1CNR1AKR1B1 | |
| Cyanide SCHEMBL28945747 | 0.88 | CA2 (0.61) | CA2HSD17B10CNR1AKR1B1FLT3 | |
| Alcohol SCHEMBL28254229 | 0.85 | CA2 (0.57) | CA2HSD17B10ALDH1A1CNR1AKR1B1 | |
| Pyridine SCHEMBL29650329 | 0.82 | CA2 (0.54) | CA2HSD17B10AHRCNR1AKR1B1 | |
| SCHEMBL14836475 | 0.79 | ALDH1A1 (0.57) | CA2HSD17B10ALDH1A1AHRKDM4E | |
| Carbazole SCHEMBL742559 | 0.79 | ALDH1A1 (0.70) | HSD17B10ALDH1A1GPR3AHRKDM4E | |
| Carbazole SCHEMBL10650068 | 0.79 | ALDH1A1 (0.70) | HSD17B10ALDH1A1GPR3AHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348268-B | Substituted carbazole-indoles sulfonate derivatives and its preparation method and application | 四川大学 | 2018-11-16 | — | — | CN | claimed |
| CN-105348268-A | Substituted carbazole-indole sulfonate derivative, and preparation method therefor and use thereof | UNIV SICHUAN | 2016-02-24 | — | — | CN | claimed |
| CN-105348268-B | Substituted carbazole-indoles sulfonate derivatives and its preparation method and application | 四川大学 | 2018-11-16 | — | — | CN | disclosed |
| CN-105348268-B | Substituted carbazole-indoles sulfonate derivatives and its preparation method and application | 四川大学 | 2018-11-16 | — | — | CN | disclosed |
| CN-105348268-B | Substituted carbazole-indoles sulfonate derivatives and its preparation method and application | 四川大学 | 2018-11-16 | — | — | CN | disclosed |
| CN-105348268-A | Substituted carbazole-indole sulfonate derivative, and preparation method therefor and use thereof | UNIV SICHUAN | 2016-02-24 | — | — | CN | disclosed |
| CN-105348268-A | Substituted carbazole-indole sulfonate derivative, and preparation method therefor and use thereof | UNIV SICHUAN | 2016-02-24 | — | — | CN | disclosed |
| CN-105348268-A | Substituted carbazole-indole sulfonate derivative, and preparation method therefor and use thereof | UNIV SICHUAN | 2016-02-24 | — | — | CN | disclosed |