Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036112 | 0.88 | RAB9A (0.61) | MLYCDMEN1KMT2ANR4A2MRGPRX4 | |
| SCHEMBL15847246 | 0.85 | PTPN7 (0.57) | MLYCDMEN1KMT2ANR4A2MRGPRX4 | |
| SCHEMBL15848569 | 0.83 | MEN1 (0.60) | MEN1KMT2ANR4A2MRGPRX4GAA | |
| SCHEMBL9526863 | 0.79 | MEN1 (0.60) | MLYCDMEN1KMT2ANR4A2MAPT | |
| SCHEMBL16298245 | 0.79 | MRGPRX4 (0.66) | MEN1KMT2ANR4A2MRGPRX4MAPT | |
| SCHEMBL13561187 | 0.79 | MRGPRX4 (0.56) | MEN1KMT2ANR4A2MRGPRX4MAPT | |
| SCHEMBL28029872 | 0.78 | MRGPRX4 (0.53) | MEN1KMT2ANR4A2MRGPRX4LMNA | |
| SCHEMBL5261051 | 0.78 | MLYCD (0.80) | MLYCDMEN1KMT2AMRGPRX4PLA2G1B | |
| SCHEMBL30661718 | 0.77 | MLYCD (0.65) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL23447721 | 0.76 | MLYCD (0.77) | MLYCDMEN1KMT2APLA2G1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008354-A | Protein kinase inhibitors | ORIBASE PHARMA | 2015-10-28 | — | — | CN | disclosed |