Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MLYCD | O95822 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849523 | 0.88 | MEN1 (0.70) | RAB9ANPC1L3MBTL1LMNAMEN1 | |
| SCHEMBL28036041 | 0.88 | MLYCD (0.54) | RAB9ANPC1LIPGL3MBTL1LMNA | |
| SCHEMBL15847246 | 0.82 | PTPN7 (0.57) | RAB9ALIPGL3MBTL1LMNAMEN1 | |
| SCHEMBL16298245 | 0.81 | MRGPRX4 (0.66) | MEN1KMT2AMAPTMRGPRX4NR4A2 | |
| SCHEMBL5261051 | 0.80 | MLYCD (0.80) | RAB9AL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL3571475 | 0.80 | BACE1 (0.60) | RAB9ANPC1L3MBTL1LMNAMEN1 | |
| SCHEMBL3235987 | 0.80 | BACE1 (0.60) | RAB9ANPC1L3MBTL1LMNAMEN1 | |
| SCHEMBL3572811 | 0.80 | BACE1 (0.60) | RAB9ANPC1L3MBTL1LMNAMEN1 | |
| SCHEMBL5178260 | 0.79 | LMNA (0.65) | RAB9ANPC1L3MBTL1LMNAMEN1 | |
| SCHEMBL30661718 | 0.79 | MLYCD (0.65) | RAB9ANPC1L3MBTL1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008354-A | Protein kinase inhibitors | ORIBASE PHARMA | 2015-10-28 | — | — | CN | disclosed |