Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27784703 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MAPK1KMT2AKDM4E | |
| SCHEMBL27904171 | 0.82 | POLB (0.50) | SMN1; SMN2ALDH1A1MAPK1POLBCYP3A4 | |
| SCHEMBL25020310 | 0.81 | MAPK1 (0.46) | SMN1; SMN2ALDH1A1MAPK1KMT2AKDM4E | |
| SCHEMBL8435296 | 0.79 | DPP4 (0.39) | SMN1; SMN2ALDH1A1MAPK1KMT2AKDM4E | |
| SCHEMBL20187406 | 0.77 | KDM4E (0.47) | SMN1; SMN2ALDH1A1MAPK1KMT2AKDM4E | |
| SCHEMBL31368738 | 0.77 | MAPK1 (0.46) | SMN1; SMN2ALDH1A1MAPK1KMT2AKDM4E | |
| SCHEMBL8356225 | 0.77 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MAPK1KMT2AKDM4E | |
| SCHEMBL21568481 | 0.77 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MAPK1KMT2AKDM4E | |
| SCHEMBL28050769 | 0.77 | CA12 (0.43) | SMN1; SMN2ALDH1A1MAPK1KMT2AKDM4E | |
| SCHEMBL19028056 | 0.76 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1MAPK1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104995173-A | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KIRIN CO LTD | 2015-10-21 | — | — | CN | disclosed |