Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036249 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1MAPK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL8356225 | 0.70 | ALDH1A1 (0.39) | ALDH1A1MAPK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL2129236 | 0.70 | ALDH1A1 (0.54) | ALDH1A1MAPK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL28088440 | 0.69 | AGBL2 (0.44) | ALDH1A1KDM4EKMT2AAGBL2GABRP | |
| SCHEMBL28607369 | 0.69 | KDM5A (0.41) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL27904171 | 0.68 | POLB (0.50) | ALDH1A1MAPK1SMN1; SMN2HSP90AA1HSP90AB1 | |
| SCHEMBL18132203 | 0.67 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KDM4EGABRPGABRD | |
| SCHEMBL29203010 | 0.67 | ALDH1A1 (0.39) | ALDH1A1MAPK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL7672020 | 0.66 | HCAR2 (0.41) | ALDH1A1MAPK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL27784703 | 0.66 | SMN1; SMN2 (0.48) | ALDH1A1MAPK1SMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356330-B1 | BIARYL KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-11-20 | — | — | EP | disclosed |