Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.58 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036978 | 0.85 | GPR119 (0.53) | CHRNB2CHRNA4GPR119CARM1PRMT6 | |
| SCHEMBL28037360 | 0.85 | CHRNB2 (0.54) | CHRNB2CHRNA4CARM1PRMT6SIGMAR1 | |
| SCHEMBL20758197 | 0.84 | CHRNB2 (0.56) | CHRNB2CHRNA4SIGMAR1 | |
| SCHEMBL20758521 | 0.84 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRNA3 | |
| SCHEMBL28036941 | 0.82 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL1391640 | 0.79 | CHRNB2 (0.57) | CHRNB2CHRNA4CHRNA3 | |
| SCHEMBL16757792 | 0.77 | CHRNB2 (0.49) | CHRNB2CHRNA4GPR119 | |
| SCHEMBL16757877 | 0.77 | CHRNB2 (0.49) | CHRNB2CHRNA4 | |
| SCHEMBL16758161 | 0.77 | CHRNB2 (0.48) | CHRNB2CHRNA4 | |
| SCHEMBL19277455 | 0.76 | CYP4F2 (0.62) | CHRNB2CHRNA4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153119-B | Pyridine pyrimidinamine compound or pyridine pyridyl amine compound and its application | 广州必贝特医药技术有限公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-105153119-A | Pyridylpyrimidyl amine compounds or pyridylpyridyl amine compounds and application thereof | GUANGZHOU KEQIN NEW MEDICINE DESIGN CO LTD | 2015-12-16 | — | — | CN | disclosed |