SCHEMBL28037209

SCHEMBL28037209

Brc1ccc(N(c2ccc(Br)cc2)c2ccc(C=Cc3ccccc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 3/20 0.55
CYP1B1 Q16678 1/20 0.46
MAOB P27338 2/20 0.45
NFE2L2 Q16236 1/20 0.45
CYP19A1 P11511 1/20 0.45
MAOA P21397 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.42
RAB9A P51151 3/20 0.42
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
CYP2C19 P33261 2/20 0.42
HPGD P15428 1/20 0.42
NPC1 O15118 2/20 0.42
APP P05067 1/20 0.42
HDAC1 Q13547 1/20 0.41
TRPA1 O75762 1/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL273653 0.96 RELA (0.50) RELACYP1B1MAOBNFE2L2CYP19A1
SCHEMBL275922 0.96 RELA (0.50) RELACYP1B1MAOBNFE2L2CYP19A1
SCHEMBL12567425 0.96 RELA (0.50) RELACYP1B1MAOBNFE2L2CYP19A1
SCHEMBL273652 0.96 RELA (0.50) RELACYP1B1MAOBNFE2L2CYP19A1
SCHEMBL4268029 0.91 ALDH1A1 (0.48) RELARAB9AALDH1A1KDM4ECYP2C19
SCHEMBL4268024 0.91 ALDH1A1 (0.48) RELARAB9AALDH1A1KDM4ECYP2C19
SCHEMBL17248030 0.91 ALDH1A1 (0.48) RELARAB9AALDH1A1KDM4ECYP2C19
SCHEMBL4585021 0.91 ALDH1A1 (0.48) RELARAB9AALDH1A1KDM4ECYP2C19
SCHEMBL12991150 0.91 ALDH1A1 (0.48) RELARAB9AALDH1A1KDM4ECYP2C19
SCHEMBL12889585 0.90 ALDH1A1 (0.50) RELACYP1B1RAB9AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103204996-B Organic electroluminescence device MERCK PATENT GMBH (DE) 2015-12-09 CN disclosed