SCHEMBL273652

SCHEMBL273652

Brc1ccc(/C=C/c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.50
APP P05067 1/20 0.45
ALDH1A1 P00352 5/20 0.45
MAPT P10636 4/20 0.45
TDP1 Q9NUW8 3/20 0.45
KDM4E B2RXH2 2/20 0.45
CYP2C19 P33261 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
RAB9A P51151 4/20 0.42
HPGD P15428 2/20 0.42
NPC1 O15118 2/20 0.42
CYP1B1 Q16678 1/20 0.42
KMT2A Q03164 3/20 0.41
MAPK1 P28482 2/20 0.41
MEN1 O00255 2/20 0.41
RXFP1 Q9HBX9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL273653 1.00 RELA (0.50) RELAAPPALDH1A1MAPTTDP1
SCHEMBL12567425 1.00 RELA (0.50) RELAAPPALDH1A1MAPTTDP1
SCHEMBL275922 1.00 RELA (0.50) RELAAPPALDH1A1MAPTTDP1
SCHEMBL28037209 0.96 RELA (0.55) RELAAPPALDH1A1MAPTTDP1
SCHEMBL12889585 0.94 ALDH1A1 (0.50) RELAAPPALDH1A1MAPTTDP1
SCHEMBL13021490 0.94 ALDH1A1 (0.50) RELAAPPALDH1A1MAPTTDP1
SCHEMBL17248030 0.91 ALDH1A1 (0.48) RELAAPPALDH1A1MAPTTDP1
SCHEMBL4268029 0.91 ALDH1A1 (0.48) RELAAPPALDH1A1MAPTTDP1
SCHEMBL4585021 0.91 ALDH1A1 (0.48) RELAAPPALDH1A1MAPTTDP1
SCHEMBL12991150 0.91 ALDH1A1 (0.48) RELAAPPALDH1A1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170244034-A1 AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2017-08-24 US disclosed
US-20170244034-A1 AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2017-08-24 US disclosed
US-20170244034-A1 AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2017-08-24 US disclosed
US-9174927-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-03 US disclosed
US-9174927-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-03 US disclosed
US-9174927-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-03 US disclosed
US-9112158-B1 Asymmetric styrene derivatives having carbazole and aniline and organic light emitting diode using the same NATIONAL TSING HUA UNIVERSITY (TW) 2015-08-18 US disclosed
US-9112158-B1 Asymmetric styrene derivatives having carbazole and aniline and organic light emitting diode using the same NATIONAL TSING HUA UNIVERSITY (TW) 2015-08-18 US disclosed
US-20150137083-A1 CONJUGATED AROMATIC DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2015-05-21 US disclosed
US-20150137083-A1 CONJUGATED AROMATIC DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2015-05-21 US disclosed
US-7732619-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-08 US disclosed
US-7732619-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-08 US disclosed
US-7732619-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-08 US disclosed
US-7459106-B2 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2008-12-02 US disclosed
US-7459106-B2 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2008-12-02 US disclosed
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
US-20070048532-A1 Organosiloxane compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-03-01 US disclosed
US-20070048532-A1 Organosiloxane compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 RELA 3551/4885APP 3012/4885ALDH1A1 4/4885
US-20070048532-A1 Organosiloxane compound and organic light-emitting device comprising the same AOX1, PPOX, SQLE RELA 3433/4885APP 3432/4885ALDH1A1 195/4885
US-20170244034-A1 AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME ARNT, AHR, CYP1A1 RELA 1203/4885APP 794/4885ALDH1A1 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.