Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1416028 | 0.84 | ALDH1A1 (0.45) | TSHRMEN1KMT2ASPHK2NPC1 | |
| SCHEMBL3982704 | 0.83 | TSHR (0.46) | MAOBTSHRKMT2ANPC1RAB9A | |
| SCHEMBL7579636 | 0.81 | RAB9A (0.55) | NPC1RAB9A | |
| SCHEMBL4351632 | 0.81 | HTT (0.49) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28900428 | 0.81 | ACE (0.47) | — | |
| SCHEMBL1416190 | 0.80 | HPGD (0.53) | CYP1A2TSHRNPC1RAB9AKDM4E | |
| SCHEMBL5965196 | 0.80 | TSHR (0.60) | TSHRKMT2ARAB9A | |
| SCHEMBL4904390 | 0.80 | GAA (0.39) | CYP1A2MEN1BLMPMP22KMT2A | |
| SCHEMBL3984572 | 0.79 | SPHK2 (0.42) | CYP1A2TSHRSPHK2KDM4E | |
| SCHEMBL14937955 | 0.79 | TSHR (0.42) | TSHRMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164124-A | Compounds and compositions for treating parasitic diseases | NOVARTIS AG | 2015-12-16 | — | — | CN | disclosed |