Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1416028 | 0.90 | ALDH1A1 (0.45) | HTTALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL5965196 | 0.85 | TSHR (0.60) | HTTHPGDRAB9ATSHRPOLB | |
| SCHEMBL14938127 | 0.84 | ALOX15 (0.51) | HTTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14937955 | 0.84 | TSHR (0.42) | HTTALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL9771647 | 0.84 | ATM (0.54) | HTTTSHRHIF1AMEN1KMT2A | |
| SCHEMBL5006927 | 0.84 | NAAA (0.58) | HTTALDH1A1HPGDTSHRMEN1 | |
| SCHEMBL7585175 | 0.83 | NAAA (0.60) | HTTALDH1A1HPGDTSHR | |
| SCHEMBL11836338 | 0.83 | NAAA (0.60) | HTTALDH1A1HPGDTSHR | |
| SCHEMBL9771503 | 0.83 | NAAA (0.60) | HTTALDH1A1HPGDTSHR | |
| SCHEMBL9768773 | 0.83 | NAAA (0.60) | HTTALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |