Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 7/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 7/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.41 |
| ▸ | DRD4 | P21917 | 9/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036953 | 0.85 | CARM1 (0.43) | CARM1PRMT6SIGMAR1DRD4TMEM97 | |
| SCHEMBL28037374 | 0.83 | CARM1 (0.42) | CARM1PRMT6SIGMAR1DRD4TMEM97 | |
| SCHEMBL28037413 | 0.82 | CARM1 (0.39) | CARM1PRMT6SIGMAR1DRD4TMEM97 | |
| SCHEMBL28037371 | 0.81 | CARM1 (0.43) | CARM1PRMT6SIGMAR1TMEM97PRMT8 | |
| SCHEMBL25341936 | 0.81 | GABRP (0.43) | — | |
| SCHEMBL29457485 | 0.81 | GABRP (0.43) | — | |
| SCHEMBL20758456 | 0.80 | CHRM2 (0.43) | CARM1PRMT6SIGMAR1DRD4TMEM97 | |
| SCHEMBL28036942 | 0.79 | CARM1 (0.44) | CARM1PRMT6SIGMAR1TMEM97PRMT8 | |
| SCHEMBL18291483 | 0.77 | MEN1 (0.42) | DRD4DRD3ALDH1A1 | |
| SCHEMBL28823133 | 0.73 | GPR119 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153119-B | Pyridine pyrimidinamine compound or pyridine pyridyl amine compound and its application | 广州必贝特医药技术有限公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-105153119-A | Pyridylpyrimidyl amine compounds or pyridylpyridyl amine compounds and application thereof | GUANGZHOU KEQIN NEW MEDICINE DESIGN CO LTD | 2015-12-16 | — | — | CN | disclosed |