Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 11/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 11/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20758456 | 0.86 | CHRM2 (0.43) | CARM1PRMT6SIGMAR1TMEM97HRH3 | |
| SCHEMBL28037413 | 0.85 | CARM1 (0.39) | CARM1PRMT6SIGMAR1TMEM97HRH3 | |
| SCHEMBL28036942 | 0.85 | CARM1 (0.44) | CARM1PRMT6SIGMAR1TMEM97HRH3 | |
| SCHEMBL28037371 | 0.84 | CARM1 (0.43) | CARM1PRMT6SIGMAR1TMEM97HRH3 | |
| SCHEMBL25341936 | 0.84 | GABRP (0.43) | PIK3CAMTOR | |
| SCHEMBL29457485 | 0.84 | GABRP (0.43) | PIK3CAMTOR | |
| SCHEMBL23330163 | 0.84 | CARM1 (0.48) | CARM1PRMT6SIGMAR1TMEM97HRH3 | |
| SCHEMBL28037364 | 0.83 | CARM1 (0.43) | CARM1PRMT6SIGMAR1TMEM97PRMT8 | |
| SCHEMBL28823133 | 0.76 | GPR119 (0.50) | — | |
| SCHEMBL1126048 | 0.75 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153119-A | Pyridylpyrimidyl amine compounds or pyridylpyridyl amine compounds and application thereof | GUANGZHOU KEQIN NEW MEDICINE DESIGN CO LTD | 2015-12-16 | — | — | CN | disclosed |