Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 5/20 | 0.43 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694309 | 0.76 | HPGD (0.58) | SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL27150944 | 0.76 | HTR1E (0.63) | DPP8DPP4DPP9DPP7METAP2 | |
| Hydrochloric Acid SCHEMBL27150943 | 0.76 | HTR1E (0.63) | DPP8DPP4DPP9DPP7METAP2 | |
| SCHEMBL28037278 | 0.75 | TAAR1 (0.50) | — | |
| SCHEMBL8127206 | 0.75 | TAAR1 (0.50) | — | |
| SCHEMBL8127204 | 0.75 | TAAR1 (0.50) | — | |
| SCHEMBL3760383 | 0.75 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2HTTMAPT | |
| SCHEMBL3769622 | 0.74 | HPGD (0.56) | SMN1; SMN2LMNARAB9A | |
| SCHEMBL28037694 | 0.73 | TAAR1 (0.37) | DPP8DPP4DPP9DPP7GLS | |
| SCHEMBL6715808 | 0.72 | KMT2A (0.67) | KMT2AMEN1SMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164124-A | Compounds and compositions for treating parasitic diseases | NOVARTIS AG | 2015-12-16 | — | — | CN | disclosed |