Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.52 |
| ▸ | PYGL | P06737 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715815 | 1.00 | KMT2A (0.67) | KMT2ATSHRPOLBSIGMAR1GRIN2D | |
| SCHEMBL6723497 | 1.00 | KMT2A (0.67) | KMT2ATSHRPOLBSIGMAR1GRIN2D | |
| Formic Acid SCHEMBL6717387 | 0.93 | TSHR (0.61) | KMT2ATSHRPOLBSIGMAR1GRIN2D | |
| SCHEMBL6723616 | 0.84 | EPHX1 (0.60) | KMT2ATSHRPOLBPYGLMEN1 | |
| SCHEMBL6824922 | 0.82 | KMT2A (0.63) | KMT2ATSHRPOLBSIGMAR1GRIN2D | |
| SCHEMBL7067161 | 0.81 | KMT2A (0.62) | KMT2ATSHRPOLBSIGMAR1GRIN2D | |
| SCHEMBL813710 | 0.79 | KMT2A (0.79) | KMT2ATSHRTDP1MEN1HTT | |
| SCHEMBL25112033 | 0.78 | PIK3CA (0.47) | KMT2ATSHRPYGLSMN1; SMN2 | |
| SCHEMBL7360425 | 0.78 | METAP2 (0.61) | KMT2ATSHRP2RX7 | |
| SCHEMBL2751737 | 0.77 | KMT2A (0.76) | KMT2ATSHRTDP1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152740-A1 | Arylglycine derivatives for use as glycine transport inhibitors | NPS ALLELIX CORPORATION (CA) | 2004-08-05 | — | — | US | disclosed |
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152740-A1 | Arylglycine derivatives for use as glycine transport inhibitors | SLC1A2, SLC6A7, SLC1A1 | KMT2A 2020/4885TSHR 3060/4885POLB 4182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.