Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093881 | 0.84 | HTR1A (0.52) | HSP90AA1ELANEHTR1AADRA1DADRA1A | |
| SCHEMBL8683168 | 0.82 | CA12 (0.55) | POLBSMN1; SMN2ALDH1A1KDM4EALOX15 | |
| SCHEMBL28037513 | 0.80 | KMT2A (0.52) | MEN1NPC1RAB9AKMT2ATAAR1 | |
| SCHEMBL6034660 | 0.79 | RXRA (0.56) | NPC1RAB9AHTR1AADRA1DADRA1A | |
| SCHEMBL6306093 | 0.77 | HSP90AA1 (0.55) | TAAR1HSP90AA1ADRA1ASMN1; SMN2FAAH | |
| SCHEMBL29431297 | 0.77 | HSD17B10 (0.61) | MEN1NPC1RAB9AKMT2ATAAR1 | |
| SCHEMBL155982 | 0.77 | HSD17B10 (0.61) | MEN1NPC1RAB9AKMT2ATAAR1 | |
| SCHEMBL6300999 | 0.76 | HSP90AA1 (0.50) | MEN1NPC1RAB9AKMT2AHSP90AA1 | |
| SCHEMBL621779 | 0.76 | HTR1A (0.58) | TAAR1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3728677 | 0.76 | LTA4H (0.52) | TAAR1HSP90AA1HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017246-A | Benzo-azepine compound and preparation method and medicine application thereof | UNIV FUDAN | 2015-11-04 | — | — | CN | disclosed |