Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18652178 | 0.80 | LOXL2 (0.49) | LOXL2CYP4F2CYP4A11MRGPRX4SLC7A5 | |
| SCHEMBL4446686 | 0.78 | LOXL2 (0.70) | LOXL2CYP4F2CYP4A11MRGPRX4SLC7A5 | |
| SCHEMBL27962222 | 0.78 | LOXL2 (0.47) | LOXL2CYP4F2CYP4A11MRGPRX4SLC7A5 | |
| SCHEMBL27666815 | 0.75 | TSHR (0.52) | LOXL2CYP4F2CYP4A11 | |
| SCHEMBL22019046 | 0.74 | SLC7A5 (0.62) | LOXL2CYP4F2CYP4A11MRGPRX4SLC7A5 | |
| SCHEMBL1421808 | 0.73 | FOLH1 (0.66) | MRGPRX4FOLH1NR4A2 | |
| SCHEMBL27924009 | 0.73 | SLC7A5 (0.47) | LOXL2CYP4F2CYP4A11SLC7A5 | |
| SCHEMBL481109 | 0.73 | LOXL2 (0.62) | LOXL2CYP4F2CYP4A11MRGPRX4SLC7A5 | |
| SCHEMBL3870676 | 0.73 | LMNA (0.56) | — | |
| SCHEMBL4980546 | 0.72 | CYP3A4 (0.50) | LOXL2CYP4F2CYP4A11SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105051037-A | Sphingosine-1-phosphate receptor agonists, method for the preparation thereof and pharmaceutical compositions comprising the same as active agent | LG LIFE SCIENCES LTD | 2015-11-11 | — | — | CN | disclosed |