Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085775 | 0.90 | TSHR (0.51) | LMNASMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL1336621 | 0.86 | ALDH1A1 (0.57) | LMNAGAASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL28619132 | 0.86 | ALDH1A1 (0.57) | LMNAGAASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL27934857 | 0.86 | ALDH1A1 (0.57) | LMNAGAASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4194919 | 0.85 | LMNA (0.56) | LMNAGAASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL28008327 | 0.84 | LMNA (0.54) | LMNAGAASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL28008234 | 0.83 | LMNA (0.53) | LMNAGAASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL1119144 | 0.80 | LMNA (0.67) | LMNAGAASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL27916231 | 0.79 | TDP1 (0.58) | LMNASMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL9723758 | 0.78 | ALDH1A1 (0.51) | LMNAGAASMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377811-A | Cyanostilbenes | ROLIC AG | 2016-03-02 | — | — | CN | disclosed |