Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5196952 | 0.83 | AKR1C1 (0.56) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL29266081 | 0.83 | THRB (0.46) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL28619132 | 0.82 | ALDH1A1 (0.57) | TDP1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL1336621 | 0.82 | ALDH1A1 (0.57) | TDP1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL27934857 | 0.82 | ALDH1A1 (0.57) | TDP1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL27986155 | 0.82 | TDP1 (0.53) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL4213521 | 0.80 | ALDH1A1 (0.60) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL4213513 | 0.80 | ALDH1A1 (0.60) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL28037704 | 0.79 | LMNA (0.61) | TDP1KMT2ASLC6A2ALDH1A1LMNA | |
| SCHEMBL27144 | 0.79 | ALDH1A1 (0.68) | TDP1KMT2ASLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103274981-A | Synthetic method for 3-hydroxyl multi-substituted tetrahydropyrrole derivative | UNIV EAST CHINA NORMAL | 2013-09-04 | — | — | CN | claimed |
| CN-103274957-A | Synthetic method for alpha,alpha-disubstituted amino acid derivative | UNIV EAST CHINA NORMAL | 2013-09-04 | — | — | CN | claimed |
| CN-103274981-A | Synthetic method for 3-hydroxyl multi-substituted tetrahydropyrrole derivative | UNIV EAST CHINA NORMAL | 2013-09-04 | — | — | CN | disclosed |
| CN-103274957-A | Synthetic method for alpha,alpha-disubstituted amino acid derivative | UNIV EAST CHINA NORMAL | 2013-09-04 | — | — | CN | disclosed |