Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057741 | 0.84 | HCAR2 (0.44) | ALPLHCAR3HCAR2NOS2 | |
| SCHEMBL1527555 | 0.82 | HCAR2 (0.53) | ALPLTP53HCAR3HCAR2 | |
| Hydrochloric Acid SCHEMBL27449787 | 0.81 | HCAR2 (0.51) | ALPLTP53HCAR3HCAR2 | |
| SCHEMBL4790447 | 0.78 | HCAR2 (0.54) | ALPLTP53HCAR3HCAR2 | |
| SCHEMBL7008825 | 0.77 | ALPL (0.50) | ALDH1A1MAPTLMNAALPLGAA | |
| SCHEMBL6622541 | 0.73 | PLA2G10 (0.42) | ALDH1A1MAPTLMNAALPLGAA | |
| SCHEMBL23950171 | 0.73 | ALPL (0.50) | ALDH1A1MAPTLMNAALPLGAA | |
| SCHEMBL2824535 | 0.73 | ALPL (0.53) | ALDH1A1MAPTLMNAALPLGAA | |
| SCHEMBL1092 | 0.71 | HCAR3 (0.54) | ALPLTP53HCAR3HCAR2KDM4E | |
| SCHEMBL1456258 | 0.71 | MAPK1 (0.57) | MAPTLMNAALPLGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596910-B | Androgen receptor modulating compounds | ORION CORP. (FI) | 2015-11-25 | — | — | CN | disclosed |
| CN-105061313-A | Androgen receptor modulating compounds | ORION CORP | 2015-11-18 | — | — | CN | disclosed |