SCHEMBL8223149

SCHEMBL8223149

CNC(=S)N/N=C(C)/C(C)=N/NC(=S)NC

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 5/20 0.50
GAA P10253 5/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 6/20 0.44
ALOX12 P18054 3/20 0.44
MAPT P10636 3/20 0.44
TOP2A P11388 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
KDM4E B2RXH2 2/20 0.38
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
NPC1 O15118 1/20 0.32
GLA P06280 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16701390 1.00 NPSR1 (0.50) NPSR1GAATDP1ALDH1A1ALOX12
SCHEMBL16701389 1.00 NPSR1 (0.50) NPSR1GAATDP1ALDH1A1ALOX12
SCHEMBL23077790 0.93 NPSR1 (0.46) NPSR1GAATDP1ALDH1A1ALOX12
SCHEMBL17326362 0.91 NPSR1 (0.44) NPSR1GAATDP1ALDH1A1ALOX12
SCHEMBL12727663 0.89 NPSR1 (0.43) NPSR1GAATDP1ALDH1A1ALOX12
SCHEMBL19704484 0.89 GAA (0.43) NPSR1GAATDP1ALDH1A1ALOX12
SCHEMBL20886084 0.87 GAA (0.42) NPSR1GAATDP1ALDH1A1ALOX12
SCHEMBL21761510 0.87 GAA (0.42) NPSR1GAATDP1ALDH1A1ALOX12
SCHEMBL20776950 0.85 NPSR1 (0.44) NPSR1GAATDP1ALDH1A1ALOX12
SCHEMBL1642339 0.85 NPSR1 (0.44) NPSR1GAATDP1ALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 955 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636867-B2 Biaxially oriented polypropylene-based multilayer film BOREALIS AG (AT) 2026-05-26 US claimed
CN-121045338-B Cyclic peptide targeting CAIX and preparation method and application thereof 原子高科股份有限公司 2026-05-19 CN claimed
WO-2026097940-A1 RADIONUCLIDE-LABELED POLYMER, PREPARATION METHOD THEREFOR, AND USETHEREOF 成都社泰医疗科技有限公司 2026-05-15 WO claimed
WO-2026098441-A1 COMPOSITION AND METHOD FOR CANCER TREATMENT USING POLYPEPTIDE CONJUGATES SUZHOU SMARTNUCLIDE BIOPHARMACEUTICAL CO., LTD. (CN) 2026-05-15 WO claimed
EP-4735055-A1 UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR (UPAR)-PET/CT IN BRAIN TUMOURS Curasight A/S (DK) 2026-05-06 EP claimed
WO-2026089950-A1 ARTICLES CONTAINING COMPOSTABLE HOT MELT ADHESIVES HENKEL AG & CO. KGAA (DE) 2026-04-30 WO claimed
US-12604413-B2 Method for producing electrical circuitry on filled organic polymers DUPONT ELECTRONICS, INC. 2026-04-14 US claimed
US-12601731-B2 Method to determine API gravity of sulfur-rich marine oils using aromatic compound chemistry SAUDI ARABIAN OIL COMPANY (SA) 2026-04-14 US claimed
US-20260041617-A1 COSMETIC COMPOSITION APPLICABLE TO THE SKIN AND BASED ON A VOLATILE MIXTURE OF ALKANES BIOSYNTHIS (FR) 2026-02-12 US claimed
EP-4448020-B1 UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR (UPAR)-PET/CT IN NEUROENDOCRINE NEOPLAMS CURASIGHT AS (DK) 2026-02-04 EP claimed
CN-216855103-U Inflatable sponge baby air cushion 易护宝(上海)医疗产品有限公司 2022-07-01 CN claimed
WO-2022117454-A1 UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR TARGETED RADIOLABELED PEPTIDE CONJUGATES RIGSHOSPITALET (DK) 2022-06-09 WO claimed
EP-4008762-A1 DURABLE LUBRICATING FLUIDS FOR ELECTRIC VEHICLES Afton Chemical Corporation (US) 2022-06-08 EP claimed
CN-114574270-A Durable lubricating fluid for electric vehicles 雅富顿化学公司 2022-06-03 CN claimed
US-20220169945-A1 DURABLE LUBRICATING FLUIDS FOR ELECTRIC VEHICLES AFTON CHEMICAL CORPORATION 2022-06-02 US claimed
CN-112574280-B Double-enzyme system probe and application thereof 北京大学第一医院 2022-05-17 CN claimed
US-11326123-B1 Durable lubricating fluids for electric vehicles AFTON CHEMICAL CORPORATION (US) 2022-05-10 US claimed
CN-114163499-A Cadherin inhibitor and preparation method and application thereof 浙江大学 2022-03-11 CN claimed
US-20220042267-A1 DEFORMED PILE SHAFT FOR PROVIDING GRIPPING CONTACT WITH A SUPPORTING MEDIUM AND RESISTING THE SUPPORTING MEDIUM FROM SHEARING STROYER BENJAMIN G (US) 2022-02-10 US claimed
CN-114014843-A PSMA (patterned beam-selective membrane antigen) targeted nuclide/fluorescent bimodal ligand, molecular probe and application 北京大学第一医院 2022-02-08 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041617-A1 COSMETIC COMPOSITION APPLICABLE TO THE SKIN AND BASED ON A VOLATILE MIXTURE OF ALKANES CUTA, AP2M1, LBR NPSR1 4105/4885GAA 3527/4885TDP1 1620/4885
US-12601731-B2 Method to determine API gravity of sulfur-rich marine oils using aromatic compound chemistry SRMS, MSMO1, PIM2 NPSR1 2824/4885GAA 3331/4885TDP1 3225/4885
US-12636867-B2 Biaxially oriented polypropylene-based multilayer film POP1, MSH2, PMS2 NPSR1 4327/4885GAA 4714/4885TDP1 1514/4885
US-12604413-B2 Method for producing electrical circuitry on filled organic polymers CHRNA7, CHRNA4, CHRNB4 NPSR1 2508/4885GAA 4267/4885TDP1 2274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.