Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431610 | 0.86 | RXFP1 (0.66) | SMN1; SMN2PTGS1NPC1RAB9AMAPT | |
| SCHEMBL28037920 | 0.85 | RXFP1 (0.69) | PTGS1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8401893 | 0.83 | PTGS1 (0.60) | SMN1; SMN2PTGS1NPC1RAB9AMAOB | |
| SCHEMBL8052702 | 0.83 | KMT2A (0.63) | RAB9AMAPTLMNATDP1TP53 | |
| SCHEMBL31092080 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2PTGS1NPC1RAB9AMAOB | |
| SCHEMBL8431673 | 0.80 | SMN1; SMN2 (0.71) | SMN1; SMN2PTGS1NPC1RAB9AMAOB | |
| SCHEMBL15285327 | 0.79 | MAPT (0.62) | SMN1; SMN2PTGS1NPC1RAB9AMAPT | |
| SCHEMBL2698258 | 0.79 | P2RX1 (0.75) | SMN1; SMN2PTGS1NPC1RAB9AMAPT | |
| SCHEMBL2638776 | 0.79 | PTGS1 (0.70) | SMN1; SMN2PTGS1NPC1RAB9ALMNA | |
| SCHEMBL12700361 | 0.79 | NPC1 (0.71) | SMN1; SMN2PTGS1NPC1RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843255-A | Ethanol-reducing mouthwash formulation | 强生消费者公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-104797236-B | Oral care compositions | 麦克内尔-PPC股份有限公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-105142601-B | Oral care composition | 强生消费者公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-107260575-A | High water content oral cavity composition comprising microcrystalline cellulose and carboxymethyl cellulose | 高露洁-棕榄公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-105142601-A | Oral care compositions | JOHNSO & JOHNSON CONSUMER COMPANIES INC | 2015-12-09 | — | — | CN | disclosed |