Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.49 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133550 | 0.88 | P2RX1 (0.63) | MAPTRXFP1 | |
| SCHEMBL4431610 | 0.86 | RXFP1 (0.66) | PTGS1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL2703394 | 0.86 | LMNA (0.62) | PTGS1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL2699662 | 0.86 | RXFP1 (0.69) | PTGS1MAPTRXFP1 | |
| SCHEMBL10192623 | 0.84 | KMT2A (0.68) | PTGS1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL10282820 | 0.84 | P2RX1 (0.57) | MAPTRXFP1 | |
| SCHEMBL28038264 | 0.83 | SMN1; SMN2 (0.68) | PTGS1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL2700947 | 0.83 | RAB9A (0.62) | PTGS1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL2700957 | 0.82 | KMT2A (0.55) | PTGS1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL2699617 | 0.82 | POLB (0.55) | PTGS1RAB9AMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905090-A | IMMUNOSUPPRESSANTS AND/OR ANTIINFLAMMATORIES | ITALFARMACO S.P.A. (IT) | 1999-05-18 | — | — | US | disclosed |