SCHEMBL8052702

SCHEMBL8052702

O=C(Nc1ccccc1)c1ccccc1OBr

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.63
MAPT P10636 3/20 0.63
USP2 O75604 1/20 0.63
SGMS2 Q8NHU3 1/20 0.62
ALDH1A1 P00352 2/20 0.59
MEN1 O00255 4/20 0.58
HPGD P15428 2/20 0.58
LMNA P02545 2/20 0.58
KDM4E B2RXH2 1/20 0.58
TP53 P04637 1/20 0.58
HTT P42858 1/20 0.58
HSD17B10 Q99714 1/20 0.58
KCNK3 O14649 2/20 0.57
KCNK9 Q9NPC2 2/20 0.57
TDP1 Q9NUW8 1/20 0.56
RAB9A P51151 1/20 0.55
METAP2 P50579 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C9 P11712 1/20 0.54
ALOX12 P18054 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5049435 0.84 SGMS2 (0.64) KMT2AMAPTUSP2SGMS2ALDH1A1
SCHEMBL28038264 0.83 SMN1; SMN2 (0.68) KMT2AMAPTMEN1LMNATP53
SCHEMBL2362772 0.82 KMT2A (0.82) KMT2AMAPTALDH1A1MEN1LMNA
SCHEMBL5852391 0.82 SGMS2 (0.62) KMT2AMAPTUSP2SGMS2ALDH1A1
SCHEMBL7765883 0.82 SGMS2 (0.62) KMT2AMAPTUSP2SGMS2ALDH1A1
SCHEMBL28158230 0.82 SGMS2 (0.62) KMT2AMAPTUSP2SGMS2ALDH1A1
SCHEMBL17845885 0.81 SGMS2 (0.60) KMT2AMAPTUSP2SGMS2ALDH1A1
SCHEMBL437231 0.80 ALDH1A1 (0.87) KMT2AMAPTALDH1A1MEN1HPGD
SCHEMBL28037920 0.80 RXFP1 (0.69) MAPTCYP3A4
SCHEMBL10192623 0.79 KMT2A (0.68) KMT2AMAPTUSP2SGMS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107809908-B Aqueous antimicrobial film-forming composition for teat treatment by spray application 艺康美国股份有限公司 2021-04-13 CN claimed
CN-114787200-A Method for forming inclusion complex using hydrophilic beta-cyclodextrin derivatives and compositions thereof 塔卡美国公司 2022-07-22 CN disclosed
CN-105378075-B Histidyl-TRNA synthetase-FC conjugates ATYR 医药公司 2022-04-05 CN disclosed
CN-114057463-A Anti-crack gypsum mortar capable of effectively filling cracks or cavities and preparation method thereof 贵州开磷磷石膏综合利用有限公司 2022-02-18 CN disclosed
CN-113998973-A Rapid waterproof foaming gypsum mortar for filling house interlayer or hole and preparation method thereof 贵州开磷磷石膏综合利用有限公司 2022-02-01 CN disclosed
CN-107847635-B Carboxymethyl chitosan sponge preparation 捷锐士阿希迈公司(以奥林巴斯美国外科技术名义) 2021-08-27 CN disclosed
CN-107809908-B Aqueous antimicrobial film-forming composition for teat treatment by spray application 艺康美国股份有限公司 2021-04-13 CN disclosed
CN-111808135-A Functionally modified oligonucleotides and subunits thereof 萨勒普塔医疗公司 2020-10-23 CN disclosed
CN-110582286-A Ocular application of matrix-bound vesicles (MBV) 联邦高等教育系统匹兹堡大学 2019-12-17 CN disclosed
CN-107809908-A Aqueous antimicrobial film-forming composition for teat treatment by spray application 艺康美国股份有限公司 2018-03-16 CN disclosed
US-4126561-A ADHESIVE, WATER-INSOLUBLE PARTICLES, AND ADDTIVIES TO IMPART PROPERTIES GRANUM INCORPORATED 1978-11-21 US disclosed
US-4126563-A Composition for treating fabrics, method for making and using the same GRANUM INCORPORATED 1978-11-21 US disclosed
US-4082852-A COMPOSITION FOR SANITIZING OF SURFACES HEISS FLORIAN 1978-04-04 US disclosed
US-4077890-A Composition for treating fabrics, method for making and using the same GRANUM INCORPORATED 1978-03-07 US disclosed
US-4012326-A AMMONIUM CARBONATE OR HYDROXY CARBOXYLIC ACIDS AS DISTRIBUTING AGENTS LEVER BROTHERS COMPANY (US) 1977-03-15 US disclosed
US-3972131-A Additives for clothes dryers LEVER BROTHERS COMPANY (US) 1976-08-03 US disclosed
US-3931261-A Bromosalicylanilide biocidal agents GAF CORPORATION (US) 1976-01-06 US disclosed
US-3931261-A Bromosalicylanilide biocidal agents GAF CORPORATION (US) 1976-01-06 US disclosed
US-3931261-A Bromosalicylanilide biocidal agents GAF CORPORATION (US) 1976-01-06 US disclosed
US-3892699-A Process for inhibiting microbial growth in water-based paints OLIN CORP 1975-07-01 US disclosed