Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780541 | 0.87 | CHRM3 (0.54) | CHRM3CHRM1CHRM4CHRM5CHRM2 | |
| Hydrochloric Acid SCHEMBL28120286 | 0.84 | PKM (0.56) | CHRM3CHRM1CHRM4CHRM5CHRM2 | |
| SCHEMBL28038407 | 0.83 | CHRM3 (0.50) | CHRM3CHRM1CHRM4CHRM5CHRM2 | |
| SCHEMBL11034253 | 0.80 | MAPT (0.52) | CHRM3CHRM1CHRM4CHRM5CHRM2 | |
| SCHEMBL28997007 | 0.78 | BCHE (0.36) | CHRM3CHRM1CHRM4CHRM5CHRM2 | |
| SCHEMBL2312935 | 0.78 | LMNA (0.49) | PKMKMT2ALMNA | |
| SCHEMBL27659177 | 0.76 | CHRM3 (0.45) | CHRM3CHRM1CHRM4CHRM5CHRM2 | |
| SCHEMBL27636857 | 0.75 | MEN1 (0.48) | CHRM3CHRM1CHRM2RAB9ASMN1; SMN2 | |
| SCHEMBL27928038 | 0.74 | MAPT (0.50) | CHRM3CHRM1CHRM4CHRM5KMT2A | |
| SCHEMBL23064984 | 0.74 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103435-B | The purposes of azaindole acetogenin and they as prostaglandin D 2 receptor regulator | 爱杜西亚药品有限公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-106103435-A | Azaindole acetogenin and they are as the purposes of prostaglandin D 2 receptor conditioning agent | 埃科特莱茵药品有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105142639-A | IRAK inhibitors and uses thereof | NIMBUS IRIS INC | 2015-12-09 | — | — | CN | disclosed |