Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19703133 | 0.88 | HTR2C (0.57) | HTR2CSLC6A3HTR1ASLC6A2SLC6A4 | |
| SCHEMBL22062953 | 0.87 | MEN1 (0.46) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL27845122 | 0.81 | CA1 (0.46) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8109922 | 0.78 | HTR2C (0.41) | MEN1KMT2AHTR2CSLC6A3HTR1A | |
| SCHEMBL29639264 | 0.78 | HTR2C (0.53) | MEN1KMT2AHTR2CSLC6A3HTR1A | |
| SCHEMBL16951549 | 0.78 | HTR2C (0.46) | HTR2CSLC6A3HTR1ASLC6A2SLC6A4 | |
| SCHEMBL7779150 | 0.78 | MEN1 (0.35) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4439192 | 0.78 | NOTUM (0.39) | KMT2ATAS1R3TAS1R1TAS1R2SLC6A3 | |
| SCHEMBL2046629 | 0.77 | HTR1A (0.50) | HTR2CSLC6A3HTR1ASLC6A2SLC6A4 | |
| SCHEMBL28092534 | 0.77 | HTR2C (0.43) | HTR2CSLC6A3HTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097364-B | Spiro-piperidine derivatives as S1P modulators | ABBOTT HEALTHCARE PRODUCTS B.V. (NL) | 2015-11-25 | — | — | CN | disclosed |