Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.37 |
| ▸ | FEN1 | P39748 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951549 | 0.80 | HTR2C (0.46) | HTR2CALOX5APFEN1DRD2HTR1A | |
| SCHEMBL29639264 | 0.80 | HTR2C (0.53) | HTR2CDRD2MEN1KMT2AHTR1A | |
| SCHEMBL16951546 | 0.78 | HTR2C (0.40) | HTR2CALOX5APFEN1DRD2MEN1 | |
| SCHEMBL27845122 | 0.78 | CA1 (0.46) | HTR2CALOX5APFEN1DRD2MEN1 | |
| SCHEMBL28092534 | 0.78 | HTR2C (0.43) | HTR2CALOX5APFEN1HTR1ASLC6A2 | |
| SCHEMBL28038757 | 0.78 | MEN1 (0.42) | HTR2CALOX5APFEN1MEN1KMT2A | |
| SCHEMBL2046629 | 0.78 | HTR1A (0.50) | HTR2CALOX5APFEN1HTR1ASLC6A2 | |
| SCHEMBL16962726 | 0.76 | TDP1 (0.39) | HTR2CALOX5APFEN1DRD2MEN1 | |
| Methylene Chloride SCHEMBL28790522 | 0.74 | CA1 (0.42) | HTR2CALOX5APFEN1DRD2MEN1 | |
| SCHEMBL16958180 | 0.74 | MEN1 (0.41) | HTR2CALOX5APFEN1DRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |