Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039099 | 0.92 | ALDH1A1 (0.46) | ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL28039101 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL6152726 | 0.84 | POLB (0.44) | ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL9322076 | 0.83 | MGLL (0.51) | ALDH1A1HPGDSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL10337054 | 0.83 | MGLL (0.51) | ALDH1A1HPGDSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL7584692 | 0.79 | MAPT (0.42) | ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL28038815 | 0.77 | KMT2A (0.38) | ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL3049742 | 0.75 | TP53 (0.49) | ALDH1A1KMT2ALMNAMEN1PKM | |
| SCHEMBL11425982 | 0.75 | TSHR (0.51) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL6835143 | 0.74 | ALDH1A1 (0.71) | ALDH1A1HPGDSMN1; SMN2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105051004-A | Novel prodrugs and methods of use thereof | AUCKLAND UNISERVICES LTD | 2015-11-11 | — | — | CN | claimed |
| CN-105051004-A | Novel prodrugs and methods of use thereof | AUCKLAND UNISERVICES LTD | 2015-11-11 | — | — | CN | disclosed |