SCHEMBL28038952

SCHEMBL28038952

CCOc1ccc(O)c(F)c1F.CCOc1ccc(O)c(F)c1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ESR1 P03372 1/20 0.44
PDE4A P27815 2/20 0.41
PDE4B Q07343 2/20 0.41
PDE4C Q08493 2/20 0.41
PDE4D Q08499 2/20 0.41
ALOX5 P09917 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
TOP2A P11388 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
ABL1 P00519 1/20 0.39
ABCB1 P08183 1/20 0.39
BCR P11274 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL423475 1.00 ALDH1A1 (0.46) ALDH1A1MEN1KMT2AESR1PDE4A
Benzene SCHEMBL28823441 0.96 ALDH1A1 (0.43) ALDH1A1MEN1KMT2AESR1PDE4A
SCHEMBL1659868 0.92 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AESR1PDE4A
SCHEMBL17527769 0.86 L3MBTL1 (0.48) ALDH1A1MEN1KMT2AL3MBTL1KDM4E
SCHEMBL2233394 0.86 MAPT (0.41) ALDH1A1MEN1KMT2AESR1PDE4D
SCHEMBL1243321 0.84 ESR1 (0.48) ESR1L3MBTL1CYP1A2CYP2D6CYP2C19
SCHEMBL19442805 0.84 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AESR1PDE4A
SCHEMBL2882336 0.84 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AESR1PDE4A
SCHEMBL1066407 0.83 L3MBTL1 (0.46) ALDH1A1MEN1KMT2AL3MBTL1KDM4E
SCHEMBL9419349 0.83 ESR1 (0.48) ALDH1A1MEN1KMT2AESR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105044263-A Gas chromatography test method for 4-ethoxy-2, 3-difluorophenol CHINA SYNCHEM TECHNOLOGY CO LTD 2015-11-11 CN disclosed