Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473729 | 0.84 | THRB (0.57) | KDM4EALDH1A1SMN1; SMN2GAAEIF2AK2 | |
| SCHEMBL15239149 | 0.84 | THRB (0.57) | KDM4EALDH1A1SMN1; SMN2GAAEIF2AK2 | |
| SCHEMBL15239365 | 0.84 | THRB (0.57) | KDM4EALDH1A1SMN1; SMN2GAAEIF2AK2 | |
| SCHEMBL28039773 | 0.82 | ALDH1A1 (0.57) | KDM4EALDH1A1SMN1; SMN2GAADPP4 | |
| SCHEMBL16848327 | 0.82 | ALDH1A1 (0.61) | KDM4EALDH1A1HDAC8 | |
| SCHEMBL16848326 | 0.82 | ALDH1A1 (0.61) | KDM4EALDH1A1HDAC8 | |
| SCHEMBL751456 | 0.78 | MAPT (0.60) | ALDH1A1SMN1; SMN2GAAPOLBCYP1A1 | |
| SCHEMBL751457 | 0.78 | MAPT (0.60) | ALDH1A1SMN1; SMN2GAAPOLBCYP1A1 | |
| SCHEMBL15145284 | 0.78 | LMNA (0.59) | KDM4EALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL2036126 | 0.78 | LMNA (0.51) | KDM4EALDH1A1GAADPP4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061254-A | Synthetic method of bromine-containing azide | Hunan huateng pharmaceutical co ltd | 2015-11-18 | — | — | CN | disclosed |