SCHEMBL28039437

SCHEMBL28039437

Cc1ccc([C@@H](C)CCC=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.46
ACHE P22303 1/20 0.46
GRIA4 P48058 1/20 0.40
ALOX5 P09917 1/20 0.38
CYP2A6 P11509 1/20 0.37
SRC P12931 1/20 0.36
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
CHRNA7 P36544 1/20 0.34
ALDH1A1 P00352 2/20 0.34
TYR P14679 1/20 0.33
RIPK1 Q13546 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11340864 1.00 STAT3 (0.46) STAT3ACHEGRIA4ALOX5CYP2A6
SCHEMBL28045674 1.00 STAT3 (0.46) STAT3ACHEGRIA4ALOX5CYP2A6
SCHEMBL29026695 0.86 TYR (0.48) ALDH1A1TYRRIPK1
SCHEMBL3050047 0.82 GRIA4 (0.41) GRIA4ALDH1A1TYRRIPK1
SCHEMBL27145540 0.82 RIPK1 (0.32) STAT3ACHEGRIA4TYRRIPK1
SCHEMBL11457329 0.82 ADRB2 (0.42) CA2TYRSLC6A3
SCHEMBL17947102 0.82 ALOX5 (0.40) ALOX5
SCHEMBL27999842 0.82 HTT (0.37) CA2ALDH1A1
SCHEMBL752037 0.82 RIPK1 (0.52) RIPK1
SCHEMBL28417689 0.82 CNR1 (0.42) STAT3ACHEALOX5CYP2A6CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105198692-A Method for asymmetrically catalyzing and synthesizing (S)-curcumene UNIV CHINA AGRICULTURAL 2015-12-30 CN claimed
CN-105198692-B A kind of asymmetry catalysis synthesize the method for (S) ar-curcumene 中国农业大学 2017-03-29 CN disclosed
CN-105198692-A Method for asymmetrically catalyzing and synthesizing (S)-curcumene UNIV CHINA AGRICULTURAL 2015-12-30 CN disclosed
CN-105198692-A Method for asymmetrically catalyzing and synthesizing (S)-curcumene UNIV CHINA AGRICULTURAL 2015-12-30 CN disclosed