SCHEMBL28039489

SCHEMBL28039489

ClC(Cl)[CH]c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
ALDH1A1 P00352 4/20 0.41
MAOB P27338 2/20 0.41
CYP2A6 P11509 1/20 0.41
LMNA P02545 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MAPK1 P28482 2/20 0.35
NFE2L2 Q16236 1/20 0.35
CYP19A1 P11511 1/20 0.35
MAOA P21397 1/20 0.35
TRPA1 O75762 1/20 0.35
ALOX5 P09917 1/20 0.35
MAPT P10636 2/20 0.33
RECQL P46063 2/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
HDAC3 O15379 1/20 0.33
TNKS O95271 1/20 0.33
HDAC4 P56524 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3336700 0.78 HTR2A (0.39) TSHRALDH1A1MAOBCYP2A6LMNA
SCHEMBL3243405 0.76 TSHR (0.48) TSHRALDH1A1MAOBCYP2A6LMNA
(Z)-1,2-Diphenylethene SCHEMBL1892117 0.73 MAOB (0.58) ALDH1A1MAOBNFE2L2CYP19A1MAOA
SCHEMBL148999 0.72 MAOB (0.50) ALDH1A1MAOBLMNAMAPK1NFE2L2
SCHEMBL5455161 0.72 MAOB (0.50) ALDH1A1MAOBLMNAMAPK1NFE2L2
SCHEMBL184701 0.71 ALDH1A1 (0.41) TSHRALDH1A1MAOBCYP2A6LMNA
SCHEMBL8007285 0.71 HTR2A (0.41) TSHRALDH1A1MAOBCYP2A6LMNA
SCHEMBL315078 0.71 HTR2A (0.41) TSHRALDH1A1MAOBCYP2A6LMNA
SCHEMBL7366231 0.69 ALDH1A1 (0.39) TSHRALDH1A1MAOBCYP2A6LMNA
SCHEMBL136292 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105063103-A Method for producing chiral phenyl dichloroethanol with molds UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-11-18 CN disclosed