Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039593 | 0.85 | MAOA (0.33) | — | |
| SCHEMBL27655749 | 0.84 | ROR1 (0.30) | FYN | |
| SCHEMBL3918671 | 0.82 | TAAR1 (0.39) | — | |
| SCHEMBL27634753 | 0.81 | — | — | |
| SCHEMBL27999329 | 0.79 | MAPT (0.39) | — | |
| SCHEMBL27793390 | 0.78 | TSHR (0.41) | — | |
| SCHEMBL27868660 | 0.75 | FYN (0.33) | FYN | |
| SCHEMBL28296746 | 0.75 | FYN (0.31) | FYN | |
| SCHEMBL6655416 | 0.75 | GRM5 (0.31) | FYN | |
| SCHEMBL27982310 | 0.75 | MAPT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232118-A | Heteroaromatic compounds and their use as dopamine D1 ligands | 辉瑞大药厂 | 2016-12-14 | — | — | CN | disclosed |
| CN-105324376-A | Heteroaromatic compounds and their use as dopamine d1 ligands | PFIZER | 2016-02-10 | — | — | CN | disclosed |