Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039634 | 0.81 | MAPK1 (0.36) | MAPTKDM4ENPC1RAB9AGAA | |
| SCHEMBL29793870 | 0.76 | MT-CO2 (0.40) | MT-CO2MAPTKDM4ENPC1RAB9A | |
| SCHEMBL28242744 | 0.72 | NPC1 (0.42) | MAPTKDM4ENPC1RAB9ACYP3A4 | |
| SCHEMBL27669654 | 0.68 | POLB (0.40) | MAPTNPC1CYP3A4GAACYP1A2 | |
| SCHEMBL27736291 | 0.68 | POLB (0.40) | MAPTNPC1RAB9ACYP3A4GAA | |
| SCHEMBL10792849 | 0.67 | CYP3A4 (0.41) | MAPTKDM4ECYP3A4TSHRCNR2 | |
| SCHEMBL9904990 | 0.66 | MMP2 (0.46) | MT-CO2MAPTCYP3A4GAACYP1A2 | |
| SCHEMBL1007329 | 0.65 | MT-CO2 (0.51) | MT-CO2MAPTCYP3A4CYP2C9GAA | |
| SCHEMBL15181430 | 0.65 | MT-CO2 (0.51) | MT-CO2MAPTRAB9ACYP3A4CYP1A2 | |
| SCHEMBL5821537 | 0.65 | MT-CO2 (0.40) | MT-CO2MAPTKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085515-B | Hydrazide kind compound as coagulation factor xa inhibitors | 华北制药股份有限公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-105085515-A | Hydrazide compound as blood coagulation factor Xa inhibitor | NANJING MINGDE NEW DRUG RES AND DEV CO LTD | 2015-11-25 | — | — | CN | disclosed |