Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039646 | 0.81 | MT-CO2 (0.40) | MAPTKDM4ERAB9ANPC1GAA | |
| SCHEMBL28039651 | 0.72 | POLB (0.43) | L3MBTL1KDM4EHDAC3HDAC1HDAC2 | |
| SCHEMBL28276368 | 0.71 | MAPT (0.40) | MAPK1MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL4556628 | 0.69 | ALOX15 (0.40) | MAPK1PKML3MBTL1MAPTKDM4E | |
| SCHEMBL6305678 | 0.67 | ALDH1A1 (0.47) | MAPK1PKML3MBTL1MAPTALDH1A1 | |
| SCHEMBL4461545 | 0.64 | ALDH1A1 (0.43) | MAPK1MAPTALDH1A1HTTAPOBEC3A | |
| SCHEMBL31255675 | 0.63 | KDM4E (0.35) | MAPK1PKML3MBTL1MAPTKDM4E | |
| SCHEMBL4332370 | 0.63 | ALDH1A1 (0.52) | MAPK1MAPTKDM4EALDH1A1HTT | |
| SCHEMBL5018993 | 0.63 | L3MBTL1 (0.49) | L3MBTL1MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL19946333 | 0.63 | FAAH (0.47) | PKML3MBTL1ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085515-B | Hydrazide kind compound as coagulation factor xa inhibitors | 华北制药股份有限公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-105085515-A | Hydrazide compound as blood coagulation factor Xa inhibitor | NANJING MINGDE NEW DRUG RES AND DEV CO LTD | 2015-11-25 | — | — | CN | disclosed |