Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL57430 | 0.96 | LMNA (0.47) | — | |
| Acrylic Acid SCHEMBL10363189 | 0.92 | LMNA (0.44) | — | |
| Acrylic Acid SCHEMBL28540046 | 0.92 | — | — | |
| Acrylic Acid SCHEMBL27900867 | 0.92 | LMNA (0.44) | — | |
| Acrylic Acid SCHEMBL11792038 | 0.92 | LMNA (0.44) | — | |
| Acrylic Acid SCHEMBL29074164 | 0.92 | LMNA (0.44) | — | |
| Acrylic Acid SCHEMBL29508405 | 0.92 | LMNA (0.44) | — | |
| Acrylic Acid SCHEMBL28547140 | 0.92 | — | — | |
| Acrylic Acid SCHEMBL7803679 | 0.92 | LMNA (0.44) | — | |
| Acrylic Acid SCHEMBL29418960 | 0.92 | LMNA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100239621-A1 | GEL SHEET AND COSMETIC PREPARATION IN SHEET FORM USING THE SAME | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| CN-101842078-A | Gel sheet and cosmetic preparation in sheet form using the same | FUJIFILM CORP | 2010-09-22 | — | — | CN | disclosed |
| EP-2210583-A1 | GEL SHEET AND COSMETIC PREPARATION IN SHEET FORM USING THE SAME | FUJIFILM Corporation (JP) | 2010-07-28 | — | — | EP | disclosed |