Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL725651 | 0.96 | LMNA (0.47) | LMNAALDH1A1TSHRFGFR4MAPK1 | |
| Acrylic Acid SCHEMBL30474619 | 0.96 | LMNA (0.47) | LMNAALDH1A1TSHRFGFR4MAPK1 | |
| Acrylic Acid SCHEMBL10363189 | 0.92 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4MAPK1 | |
| Acrylic Acid SCHEMBL28540046 | 0.92 | — | — | |
| Acrylic Acid SCHEMBL2803992 | 0.92 | — | — | |
| Acrylic Acid SCHEMBL29418960 | 0.92 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4MAPK1 | |
| Acrylic Acid SCHEMBL28547140 | 0.92 | — | — | |
| Acrylic Acid SCHEMBL4943881 | 0.92 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4MAPK1 | |
| Acrylic Acid SCHEMBL11792038 | 0.92 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4MAPK1 | |
| Acrylic Acid SCHEMBL29516833 | 0.92 | LMNA (0.50) | LMNAALDH1A1TSHRFGFR4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001098209-A | TITANIC ACID COATING MATERIAL, DISINFECTANT, SURFACTANT, AND CATALYST | TANAKA HIDEAKI | 2001-04-10 | — | — | JP | disclosed |