SCHEMBL28040023

SCHEMBL28040023

COc1cccc(NC(=O)/C=C\C(N)=O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 4/20 0.67
MMP2 P08253 4/20 0.67
MMP9 P14780 4/20 0.67
ALDH1A1 P00352 5/20 0.62
MAPT P10636 5/20 0.62
KMT2A Q03164 4/20 0.62
MEN1 O00255 3/20 0.62
TRPV1 Q8NER1 3/20 0.62
TP53 P04637 2/20 0.62
TSHR P16473 2/20 0.62
HDAC6 Q9UBN7 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2C9 P11712 1/20 0.62
MAPK1 P28482 1/20 0.62
CYP2C19 P33261 1/20 0.62
LMNA P02545 4/20 0.61
NPC1 O15118 3/20 0.61
RAB9A P51151 3/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
HTT P42858 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30764060 0.87 MMP1 (0.72) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL6895377 0.87 MMP1 (0.72) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL6895368 0.87 MMP1 (0.72) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL11441877 0.87 MMP1 (0.72) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL7263605 0.84 ALDH1A1 (0.71) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL15709072 0.84 MMP1 (0.65) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL15708711 0.84 MMP1 (0.65) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL6586364 0.84 MMP1 (0.68) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL14678385 0.81 DDAH1 (0.68) MMP1MMP2MMP9ALDH1A1MAPT
SCHEMBL166106 0.81 TP53 (0.66) ALDH1A1KMT2ATP53TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104977808-A Black photosensitive resin composite and black matrix made from the black photosensitive resin composite DONGWOO FINE CHEM CO LTD 2015-10-14 CN disclosed