Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490871 | 0.85 | ALOX5 (0.76) | ALOX5PPARGPPARAAPPCHRM5 | |
| SCHEMBL22345345 | 0.82 | ALOX5 (0.56) | ALOX5MAPTAPPCHRM5CHRM1 | |
| SCHEMBL28040579 | 0.82 | PPARG (0.46) | ALOX5PPARGPPARAAPPCHRM5 | |
| SCHEMBL29641938 | 0.81 | ALOX5 (0.54) | ALOX5MAPTAPPCHRM5CHRM1 | |
| SCHEMBL9241128 | 0.78 | LTA4H (0.58) | ALOX5MAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL7156627 | 0.78 | PLAAT3 (0.53) | MAPTALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL491276 | 0.77 | CYP4F2 (0.59) | CHRM5CHRM1CHRM3SMN1; SMN2CYP1A2 | |
| SCHEMBL27806086 | 0.77 | APP (0.55) | APPCHRM5CHRM1CHRM3ALDH1A1 | |
| SCHEMBL28003037 | 0.77 | ATM (0.59) | APPCHRM5CHRM1CHRM3ALDH1A1 | |
| SCHEMBL490984 | 0.76 | ALOX5 (0.63) | ALOX5MAPTAPPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175262-A | Chrysotoxine bibenzyl derivative and preparation method and application thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | disclosed |