SCHEMBL280401

SCHEMBL280401

CCOC(=O)C(Br)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.56
CES2 O00748 2/20 0.55
CES1 P23141 2/20 0.55
PIN1 Q13526 1/20 0.51
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
TSHR P16473 2/20 0.47
GAA P10253 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28259601 0.98 MMP8 (0.54) MMP8CES2CES1PIN1KMT2A
SCHEMBL8849171 0.90 MMP8 (0.43) MMP8CES2CES1PIN1KMT2A
SCHEMBL2419442 0.85 LMNA (0.53) MMP8CES2CES1KMT2ANPC1
SCHEMBL6905840 0.85 MEN1 (0.46) MMP8PIN1KMT2AMEN1NPC1
SCHEMBL5543759 0.84 MAPT (0.45) MMP8PIN1KMT2AMEN1NPC1
SCHEMBL5964020 0.84 CES2 (0.60) MMP8CES2CES1PIN1KMT2A
SCHEMBL324361 0.83 KMT2A (0.47) MMP8CES2CES1KMT2AMEN1
SCHEMBL12920265 0.83 ESR1 (0.52) KMT2ASMN1; SMN2TSHRGAATDP1
SCHEMBL6287198 0.82 MMP8 (0.57) MMP8PIN1KMT2AMEN1NPC1
SCHEMBL2417875 0.82 TSHR (0.53) CES2CES1NPC1SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 857 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954994-A Method for free radical polymerization based on macro-micro reactor 南京工业大学 2025-05-09 CN claimed
CN-119859208-A Binary free radical polymerization method 上海交通大学 2025-04-22 CN claimed
CN-119859212-A Method for preparing functionalized polymer based on macro-micro reactor chemical-enzymatic method 南京工业大学 2025-04-22 CN claimed
CN-119751768-A Functionalized polyolefin-based nanoparticle as well as preparation method and application thereof 复旦大学 2025-04-04 CN claimed
CN-118389059-B Non-platinum curing release agent, chemically stable release film and preparation method thereof 扬州万润光电科技股份有限公司 2024-11-05 CN claimed
CN-118768579-A Preparation method and application of monodisperse silver nanoparticles 丽水学院 2024-10-15 CN claimed
CN-118325112-A Photocatalyst material based on Salen matrix unit and preparation method thereof, and application of photocatalyst material in polymerization inhibitor free radical polymerization 合肥工业大学 2024-07-12 CN claimed
CN-114702630-B Lignin-based polymer and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2024-07-12 CN claimed
CN-117820116-B Method for synthesizing alpha-bromophenylacetic acid ethyl ester serving as intermediate of phenthoate by solvent-free method 江苏腾龙生物药业有限公司 2024-07-05 CN claimed
CN-118221916-A Acoustic sensitizer material, preparation method and application thereof 合肥工业大学 2024-06-21 CN claimed
WO-2020131445-A1 DIRECT TO SUBSTRATE COATING VIA IN SITU POLYMERIZATION HENKEL AG & CO. KGAA (DE) 2020-06-25 WO claimed
CN-108752510-B Iron-catalyzed AGET ATRP system in biomass-based solvent under ligand-free condition and polymerization method 安徽工程大学 2020-05-19 CN claimed
US-10647056-B2 Method of additive manufacturing using photoregulated radical polymerization DOW GLOBAL TECHNOLOGIES LLC (US) 2020-05-12 US claimed
CN-110669477-A Controllable preparation method of clay-based microcapsule phase change material 淮阴工学院 2020-01-10 CN claimed
CN-107573447-B Method for preparing clean controllable polymer in situ by atom transfer radical polymerization 淮阴工学院 2019-12-20 CN claimed
CN-109111541-A A kind of preparation method of the high molecular polymer containing azido 江南大学 2019-01-01 CN claimed
WO-2018140977-A1 REACTIONS ENABLED BY THERMORESPONSIVE AND PHOTORESPONSIVE GELS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-08-02 WO claimed
EP-3042645-A1 Dental composites with improved storage stability Ivoclar Vivadent AG (LI) 2016-07-13 EP claimed
EP-0520024-B1 QUINOXALINE COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK AS (DK) 1996-06-19 EP claimed
US-4435575-A Process for preparing carboxylated organic compounds MONTEDISON S.P.A. (IT) 1984-03-06 US claimed