SCHEMBL28040223

SCHEMBL28040223

C=CC(=O)NOC.CC(C)C[O]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
ALDH1A1 P00352 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TGM2 P21980 1/20 0.33
CXCR1 P25024 1/20 0.33
CXCR2 P25025 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
PSMB11 A5LHX3 1/20 0.31
PSMA7 O14818 1/20 0.31
PSMB1 P20618 1/20 0.31
PSMA1 P25786 1/20 0.31
PSMA2 P25787 1/20 0.31
PSMA3 P25788 1/20 0.31
PSMA4 P25789 1/20 0.31
PSMB8 P28062 1/20 0.31
PSMB9 P28065 1/20 0.31
PSMA5 P28066 1/20 0.31
PSMB4 P28070 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284915 0.85
Acrylamide SCHEMBL28124376 0.79 TSHR (0.52) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL2832064 0.73 TSHR (0.50) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL2203945 0.71 TSHR (0.42) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28108434 0.71 TSHR (0.33) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL28108432 0.71 ZDHHC20 (0.51) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL8436115 0.70
Formic Acid SCHEMBL27467209 0.69 TSHR (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28108433 0.69 ALDH1A1 (0.35) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL27932093 0.68 TSHR (0.48) TSHRALDH1A1MAPK1TDP1TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110507561-A The lip composition of emulsion form and the processing method for using it OREAL 2019-11-29 CN disclosed
CN-105228701-B The device of liquid lip composition comprising inverted emulsion form and porous application component 莱雅公司 2019-10-25 CN disclosed
CN-105228701-A Comprise the device that the liquid lip composition of inverted emulsion form and porous use component OREAL 2016-01-06 CN disclosed
CN-105102069-A Lipstick compositions in emulsion form comprising specific film-forming polymers and treatment methods using same OREAL 2015-11-25 CN disclosed