Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17637643 | 0.84 | MAPT (0.73) | MAPTGAAKDM4ETHRBSMN1; SMN2 | |
| SCHEMBL3989117 | 0.81 | HTT (0.55) | MAPTGAAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL1006629 | 0.81 | ALDH1A1 (0.54) | MAPTGAAKDM4ETHRBSMN1; SMN2 | |
| SCHEMBL27633763 | 0.81 | MAPT (0.73) | MAPTGAAKDM4ETHRBSMN1; SMN2 | |
| SCHEMBL3984703 | 0.79 | ALDH1A1 (0.63) | MAPTGAAKDM4ETHRBPOLB | |
| SCHEMBL3989849 | 0.78 | ATM (0.51) | MAPTGAAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL17416148 | 0.78 | MAPT (0.50) | MAPTGAAKDM4ETHRBPOLB | |
| SCHEMBL3985920 | 0.77 | POLB (0.59) | MAPTPOLBNPC1RAB9AALOX12 | |
| SCHEMBL17637650 | 0.76 | NPC1 (0.58) | MAPTGAAKDM4ETHRBPOLB | |
| SCHEMBL11668327 | 0.76 | ALDH1A1 (0.63) | MAPTGAAKDM4ETHRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105026367-B | Method for producing isothiocyanate | 旭化成株式会社 | 2019-05-21 | — | — | CN | disclosed |
| CN-108976155-A | The manufacturing method of isothiocyanates | 旭化成株式会社 | 2018-12-11 | — | — | CN | disclosed |
| CN-105026367-A | Method for producing isothiocyanate, composition for transporting and storing N-substituted-O-substituted thiocarbamate, and isothiocyanate composition | ASAHI KASEI CHEMICALS CORP | 2015-11-04 | — | — | CN | disclosed |