Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248758 | 0.78 | GAA (0.48) | MEN1HPGDKMT2AHIF1ACYP3A4 | |
| SCHEMBL16795265 | 0.77 | HPGD (0.52) | MEN1HPGDKMT2AHIF1ACYP3A4 | |
| Acetic Acid SCHEMBL11588262 | 0.75 | CA2 (0.56) | MEN1HPGDKMT2AHIF1ACYP3A4 | |
| SCHEMBL1418003 | 0.75 | HIF1A (0.59) | MEN1HPGDKMT2AHIF1ACYP3A4 | |
| SCHEMBL5724270 | 0.75 | SETDB1 (0.57) | MEN1HPGDKMT2AHIF1ACYP3A4 | |
| SCHEMBL3185618 | 0.73 | ERCC1 (0.54) | MEN1HPGDKMT2AHIF1ACYP3A4 | |
| SCHEMBL5724332 | 0.73 | ERCC1 (0.57) | MEN1HPGDKMT2AHIF1ACYP3A4 | |
| SCHEMBL23915663 | 0.73 | OXTR (0.61) | MEN1HPGDKMT2AHIF1ACYP3A4 | |
| SCHEMBL13219436 | 0.73 | MEN1 (0.61) | MEN1HPGDKMT2AHIF1ACYP3A4 | |
| SCHEMBL12305651 | 0.73 | MEN1 (0.67) | MEN1HPGDKMT2AHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008331-B | Act on multiple prostaglandin receptors, produce the compound of general anti-inflammatory response | 阿勒根公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-105008331-A | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN INC | 2015-10-28 | — | — | CN | disclosed |